Acute Non-communicating Hydrocephalus Developed within 48 Hours in a Patient with Systemic Lupus Erythematosus
Baha Eldin Adam *
Department of Neurosurgery, Istanbul Medeniyet University, Göztepe Education and Research Hospital, Istanbul, Turkey
M. Emin Eminoğlu
Department of Neurosurgery, Istanbul Medeniyet University, Göztepe Education and Research Hospital, Istanbul, Turkey
Mehmet Erşahin
Department of Neurosurgery, Istanbul Medeniyet University, Göztepe Education and Research Hospital, Istanbul, Turkey
Abdulkadır Koçer
Department of Neurology, Istanbul Medeniyet University, Göztepe Education and Research Hospital, Istanbul, Turkey
*Author to whom correspondence should be addressed.
Abstract
Hydrocephaly is a rare manifestation of systemic lupus erythematosus [SLE], and the pathogenesis is still unclear. Some studies suggest cerebral venous thrombosis, immune complex deposition within the arachnoid villi, or direct post-inflammatory lesions of the central nervous system [CNS] as possible causes, but these remain unproven. We report a case of acute non-communicating hydrocephalus secondary to stenosis of the aqueduct of Sylvius. The condition developed within a 48-hour period as the result of cerebrovascular accident in a 40-year-old man with previously diagnosed SLE. The pathophysiologic mechanism of hydrocephalus in SLE is subject to various arguments and remains a dilemma facing researchers.
Keywords: Hydrocephalous, systemic lupus erythematous, cerebrovascular accident, pathogenesis and pathophysiology